| Masuma Mammadova, Nuru Bayramov, Zarifa Jabrailova, Minara Manafli, Mehriban Huseynova Clinical Decision Support System for Hepatocellular Carcinoma Treatment Selection |
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| Abstract. The article presents an algorithm for creating an intelligent physician decision support system regarding the initial treatment selection for hepatocellular carcinoma (HCC), which is the 5th-6th most common cancer. HCC is determined by a large number of parameters, and according to the values they can receive, resection, transplantation, ablation, embolization, systemic treatment, symptomatic treatments are selected according to the staged classical approach to the HCC treatment based on the clinical situations that arise. The large number, complexity, quantitative and qualitative character of the input parameters symbolizes the choice of treatment for HCC as a difficult formalized issue and makes the development of an intelligent system for its solution relevant. In this regard, this article solves the issue of integrating the doctors’ knowledge collected in a multidisciplinary consultation into the knowledge base of the intelligent system for the individual choice of treatment for HCC, and develops the working principle and implementation algorithm of the system’s architectural components. |
| Keywords: hepatocellular carcinoma; treatment selection; intelligent physician decision support system; descriptive model of knowledge |
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